Nanocontainer ships titan-size gene therapies and drugs into cells

Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size—even hefty ones attached to the gene-editing ...

'Dual login' mechanism found to resist fungal infection in cells

Indiana University researchers have identified a mechanism involving the body's ability to resist fungal infection. The work could help advance research on cancer therapies that use the body's own immune system to fight disease.

Precisely poking cells en masse to cure cancer

What if you could cure cancer by re-engineering patients' cells to better target and destroy their own tumors? With the advent of powerful new cellular engineering technologies, this is no longer the stuff of science fiction.

Better biosensor technology created for stem cells

A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders.

Completing DNA synthesis

The final stage of DNA replication—"termination"—occurs when two DNA copy machines advance upon each other and unwind the final stretch of DNA. This process occurs about 60,000 times per human cell cycle and is crucial ...

Cell stiffness may indicate whether tumors will invade

Engineers at MIT and elsewhere have tracked the evolution of individual cells within an initially benign tumor, showing how the physical properties of those cells drive the tumor to become invasive, or metastatic.

New CRISPR-Cas9 variant may boost precision in gene editing

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans. The new variant reduced unintended changes in DNA compared to ...

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