Hidden RNA repair mechanism discovered in humans

Ribonucleic acids (RNAs) are single-stranded molecules that play an essential role in the cells of all living organisms. As "transcripts" of our genes, mRNAs, for example, are involved in the translation of genetic information ...

Brain cells protect muscles from wasting away

While many of us worry about proteins aggregating in our brains as we age and potentially causing Alzheimer's disease or other types of neurodegeneration, we may not realize that some of the same proteins are aggregating ...

The male Y chromosome does more than we thought

New light is being shed on a little-known role of Y chromosome genes, specific to males, that could explain why men suffer differently than women from various diseases, including COVID-19.

Chocolate, tea or coffee with zinc could reduce oxidative stress

Ageing and a low life expectancy are caused, at least partly, by oxidative stress. A team of researchers led by Prof. Dr. Ivana Ivanovi-Burmazovi from the Chair of Bioinorganic Chemistry at Friedrich-Alexander-Universität ...

New infection mechanism in SARS-CoV-2 discovered

Researchers from Heidelberg Medical Faculty, Heidelberg University Hospital and German Cancer Research Center investigate molecular relationships that promote infection and spread of SARS-CoV-2. The results may provide a ...

Scientists pinpoint one way nanoparticles damage immune cells

Scientists have shown that a process known as oxidative stress is at work during encounters between certain nanoparticles and immune cells, selectively modifying proteins on macrophages, a type of immune cell. The findings, ...

Initiating DNA repair

To find out what activates SIRT6, the researchers alternately applied chemical inhibitors to human skin cells to determine which proteins were essential in getting the gene to repair the broken DNA strands. They discovered ...

Study shows stressed-out cells halt protein synthesis

(Phys.org)—Cells experience stress in multiple ways. Temperature shifts, mis-folded proteins and oxidative damage can all cause cellular stress. But whatever the form of the stress, all cells quickly stop making proteins ...

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