Researchers discover that protein switches functions to regulate DNA replication
One protein. One mechanism of action. Two biologically opposite effects.
One protein. One mechanism of action. Two biologically opposite effects.
Biotechnology
Jul 23, 2021
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2249
Cells can both survive and multiply under more stress than previously thought, shows research from the Faculty of Health and Medical Sciences.
Biotechnology
Feb 28, 2020
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773
In spore-forming bacteria, chromosomal locations of genes can couple the DNA replication cycle to critical, once-in-a-lifetime decisions about whether to reproduce or form spores. The new finding by Rice University bioengineers ...
Cell & Microbiology
Jul 9, 2015
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784
DNA replication is a tightly regulated process that ensures the precise duplication of the genome during cell proliferation. Replication origins determine where replication starts on the genome and regulate the whole genome ...
Molecular & Computational biology
Dec 27, 2019
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221
Researchers at the University of Liverpool have shown how SARS-CoV-2 viral proteases attack the host cell, and how this can be targeted to stop virus replication in cell culture using existing drugs.
Molecular & Computational biology
Sep 21, 2021
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1129
Researchers at the University of Wisconsin–Madison have described the way an enzyme and proteins interact to maintain the protective caps, called telomeres, at the end of chromosomes, a new insight into how a human cell ...
Cell & Microbiology
Aug 1, 2022
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192
If asked about clones, most people think of evil sci-fi characters. However, in real life, the word "clone" often has broader, far more positive applications. Just as office workers replicate documents by using copy machines, ...
Biotechnology
Oct 8, 2018
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14
At the same time that a cell's DNA gets duplicated, a third of it gets super-compacted into repetitive clumps called heterochromatin. This dense packing serves to repress or "silence" the DNA sequences within -- which could ...
Cell & Microbiology
Oct 16, 2011
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0
Researchers at ETH Zurich and the University of Bern have discovered a mechanism by which the corona virus manipulates human cells to ensure its own replication. This knowledge will help to develop drugs and vaccines against ...
Cell & Microbiology
Sep 14, 2020
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112
Scientists from the Hebrew University have identified the molecular basis for DNA breakage, a hallmark of cancer cells. The findings of this research have just been published in the journal Molecular Cell.
Cell & Microbiology
Jul 19, 2011
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