Breaking COVID-19's 'clutch' to stop its spread

Scripps Research chemist Matthew Disney, Ph.D., and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus' so-called "frameshifting element" to stop the virus from ...

A new strategy of cell entry for some types of parvoviruses

Researchers at the Institut national de la recherche scientifique (INRS), in collaboration with American scientists, have discovered a new parvovirus strategy for reaching the cell nucleus, where they reproduce. The results ...

Removal of a gene could render lethal poxviruses harmless

The removal of one gene renders poxviruses—a lethal family of viral infections that are known to spread from animals to humans—harmless, a new study in the journal Science Advances reports.

Viruses play critical role in evolution and survival of the species

As the world scrambles to control the growing COVID-19 coronavirus pandemic, new research in Nature Structural & Molecular Biology shows viruses also play a key evolutionary role in mammals' ability to reproduce and survive.

How a protein stops cells from attacking their own DNA

Viruses multiply by injecting their DNA into a host cell. Once it enters the intracellular fluid, this foreign material triggers a defense mechanism known as the cGAS-STING pathway. The protein cyclic GMP-AMP Synthase (cGAS), ...

Algorithm predicts the compositions of new materials

A machine-learning algorithm that can predict the compositions of trend-defying new materials has been developed by RIKEN chemists1. It will be useful for finding materials for applications where there is a trade-off between ...

Compressive shearing may start life on other planets

Massive compressive shearing forces generated by the tidal pull of Jupiter-like planets on their rocky ice-covered moons may form a natural reactor that drives simple amino acids to polymerize into larger compounds. These ...

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