Random differences between cells early in development could be the key to making different cells in the body, according to new research from a team co-led by Professor Wolf Reik. Different cell types - brain, blood, skin, ...
Cell & Microbiology
Aug 1, 2017
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28
Researchers at the Babraham Institute, EMBL's European Bioinformatics Institute (EMBL-EBI), CRUK Cambridge Institute and the Wellcome—MRC Cambridge Stem Cell Institute have provided the first single-cell epigenomic analysis ...
Cell & Microbiology
Dec 11, 2019
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254
How do neurons become neurons? They all begin as stem cells, undifferentiated and with the potential to become any cell in the body.
Cell & Microbiology
Mar 24, 2016
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19
Scientists have long sorted cells into different varieties based on their appearance under a microscope or, for differences that are more visually subtle, based on the behavior of a handful of genes. But in a bid to reveal ...
Cell & Microbiology
May 28, 2019
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66
All it takes is one molecule to reprogram an antibody-producing B cell into a scavenging macrophage. This transformation is possible, new evidence shows, because the molecule (C/EBPa, a transcription factor) "short-circuits" ...
Cell & Microbiology
Jul 30, 2015
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24
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona and the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin have revealed how cells accelerate changes to their identity, ...
Cell & Microbiology
Jun 27, 2023
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58
As plants stretch toward the summer sun, they are marching toward one of the most important decisions of their lives—when to flower. Too early, and they might miss out on key pollinators. Too late, and an early frost could ...
Biotechnology
Aug 6, 2018
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77
A new King's-led study, published in the Proceedings of the National Academy of Sciences, has found that a single factor (a protein coding gene known as Sox8) can make non-ear cells adopt ear character during embryo development. ...
Cell & Microbiology
Jul 11, 2022
1
76
High-resolution gene expression maps have been combined with single-cell genomics data to create a new resource for studying how cells adopt different identities during mammalian development. The Spatial Mouse Atlas is the ...
Cell & Microbiology
Sep 7, 2021
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16
Bioengineers at the University of California, San Diego have discovered that mouse embryos are contemplating their cellular fates in the earliest stages after fertilization when the embryo has only two to four cells, a discovery ...
Biotechnology
Nov 26, 2014
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