Histone degradation after DNA damage enhances repair

DNA damage can occur anywhere in the genome, but most DNA is wrapped around nucleosomes making it inaccessible to the repair machinery. Researchers from the Gasser group now show that DNA damage induces histone depletion, ...

Researchers create bioluminescent tag to detect DNA break repair

A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan. The international team's ...

Calcium helps build strong cells

Every time you flex your bicep or stretch your calf muscle, you put your cells under stress. Every move we make throughout the day causes our cells to stretch and deform. But this cellular deformation can be dangerous, and ...

New method reveals where DNA is at risk in the cell

Researchers at Karolinska Institutet have developed a new sequencing method that makes it possible to map how DNA is spatially organized in the cell nucleus—revealing which genomic regions are at higher risk of mutation ...

Real-time observation of enzymatic processes on DNA

DNA damage in general and DNA strand breaks in particular occur every day in all cells of the human body. This is due to internal influences such as free radicals, which are produced during inflammatory processes and cellular ...

Soy scaffolds: Breakthrough in cultivated meat production

Researchers from the Technion-Israel Institute of Technology and Aleph Farms have achieved a breakthrough in the production of cultivated meat grown outside an animal's body. In findings published today in Nature Food, soy ...

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