Adoptive T-cell therapy has revolutionized medicine. A patient's T-cells—a type of white blood cell that is part of the body's immune system—are extracted and modified in a lab and then infused back into the body, to ...
Bio & Medicine
Jun 12, 2024
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47
A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its ...
Biotechnology
Jun 10, 2024
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17
A groundbreaking study led by the USC Leonard Davis School of Gerontology in collaboration with Dominican University of California explores how small molecules derived from sea sponges affect energy production in mitochondria ...
Biochemistry
Jun 6, 2024
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43
Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA ...
Cell & Microbiology
Jun 6, 2024
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8
Some cancer drugs cause severe side effects because they are not working accurately enough. A team at the University of Würzburg led by biochemist Caroline Kisker has now discovered why.
Biochemistry
Jun 6, 2024
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5
UCLA scientists have identified a protein that plays a critical role in regulating human blood stem cell self-renewal by helping them sense and interpret signals from their environment.
Cell & Microbiology
Jun 5, 2024
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40
The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere ...
Cell & Microbiology
Jun 5, 2024
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75
Several million cells divide every second in our bodies. During nuclear division (mitosis), the genetic material must be distributed correctly and completely between the daughter cells—errors in this process can lead to ...
Cell & Microbiology
Jun 4, 2024
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10
RIKEN chemists have demonstrated a gold-nanocluster system that carries two components of a drug in a controlled ratio for maximum cancer-cell killing effect. The active drug remains safely masked until red light triggers ...
Bio & Medicine
May 30, 2024
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19
Researchers at Baylor College of Medicine and collaborating institutions have discovered that a protein called hnRNPM helps protect the integrity of the process cells use to make proteins. hnRNPM works by preventing the cell ...
Cell & Microbiology
May 29, 2024
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