Study tracks protein's role in stem cell function

MCL-1 is a member of the BCL-2 family of proteins important for blocking apoptosis, or programmed cell death. Many types of cancer cells escape the body's effort to kill them by overexpressing MCL-1.

Scientists isolate cancer stem cells using novel method

Researchers at The University of Texas at Dallas have devised a new technique to isolate aggressive cells thought to form the root of many hard-to-treat metastasized cancers—a significant step toward developing new drugs ...

Versatile sensor against tumor initiating cells

Most cancer deaths are caused by recurrent or metastatic tumors. Conventional therapies target rapidly dividing tumor cells, but are unable to eradicate the highly chemoresistant tumor initiating cells (TICs), ultimately ...

Ribosomes found to induce somatic cell pluripotency

In 2012, a Japanese research group discovered that human skin cells acquire pluripotency when introduced to lactic acid bacteria (Lactobacillus acidophilus). Now, the same group of researchers has found that the cause of ...

Breast cancer research gets a mechanical boost

One of the most puzzling questions in breast cancer research is why some tumors stay put, while rogue cells from others break free and spread to surrounding tissues, the first step toward creating a more lethal disease. Although ...

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