Statistical methods improve biological single-cell analyses

Stem cells can turn into heart cells, skin cells can mutate to cancer cells; even cells of the same tissue type exhibit small heterogeneities. Scientists use single-cell analysis to investigate these heterogeneities. But ...

Adult stem cells found to suppress cancer while dormant

Researchers at UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have discovered a mechanism by which certain adult stem cells suppress their ability to initiate skin cancer during their dormant ...

Speeding up gene discovery

Since the completion of the Human Genome Project, which identified nearly 20,000 protein-coding genes, scientists have been trying to decipher the roles of those genes. A new approach developed at MIT, the Broad Institute, ...

Targeting cancer's 'queen bees' with better tissue modeling

In many types of cancer, standard chemotherapy cures only a fraction of patients. Treatments are often too toxic to normal cells and they fail to selectively kill cancer's stem cells, which can survive treatment and, like ...

Keeping centrioles in check to ensure proper cell division

(Phys.org) —The duplication of cellular contents and their distribution to two daughter cells during cell division are amongst the most fundamental features of all life on earth. How cell division occurs and is coordinated ...

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