Unregulated cell division is a hallmark of cancer, and one of the key proteins involved in controlling cell division is called FoxM1. Abnormal activation of FoxM1 is a common feature of cancer cells and is correlated with ...
Cell & Microbiology
May 28, 2019
0
49
A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells. The cryo-EM ...
Biochemistry
Jan 29, 2016
0
20
A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in near-atomic detail, the architecture of a metabolic enzyme bound to a drug that blocks its activity. ...
General Physics
May 7, 2015
0
56
It's an ancient type of microorganism that makes up 20 per cent of the Earth's biomass, yet only now are scientists revealing the secrets of archaea.
Cell & Microbiology
Jan 5, 2015
4
31
(Phys.org) —Scientists have developed a new approach for treating a deadly brain cancer that strikes 15,000 in the United States annually and for which there is no effective long-term therapy. The researchers, from Yale ...
Bio & Medicine
Jul 2, 2013
1
0
(Phys.org) —A rare tree found in Malaysia and Borneo holds the secret to greener chemical production, according to researchers from the Research School of Chemistry.
Biochemistry
Jun 3, 2013
0
0
Transcription is a cellular process by which genetic information from DNA is copied to messenger RNA for protein production. But anticancer drugs and environmental chemicals can sometimes interrupt this flow of genetic information ...
Biochemistry
Aug 21, 2012
0
0
(PhysOrg.com) -- Researchers have achieved a feat drug developers had thought difficult, if not impossible, discovering a compound that blocks the functioning of a key developmental protein by binding to an “undruggable” ...
Jan 19, 2009
0
0
Curcumin, a natural molecule related to turmeric, has been used to treat cancer patients in cancer clinical studies. While it has documented antitumor effects, challenges involving its chemistry have caused drug development ...
Biochemistry
Oct 27, 2022
0
7
Cell-to-cell contacts are necessary for the survival of human cells under protein-damaging conditions and stress. This was one of the conclusions made by a research team working under the leadership of Lea Sistonen, Professor ...
Cell & Microbiology
Jan 16, 2020
0
5
