Research led by the University of Pennsylvania, Philadelphia, has used siRNA-based silencing of protein cyclophilin A (CyPA) to reduce tumor burden and extend the lives of patients with multiple myeloma.
The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications ...
Cell & Microbiology
Jun 15, 2022
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136
Nearly 70 percent of patients with advanced breast cancer experience skeletal metastasis, in which cancer cells migrate from a primary tumor into bone—a painful development that can cause fractures and spinal compression. ...
Analytical Chemistry
Feb 6, 2014
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1
(PhysOrg.com) -- In an important breakthrough, scientists at McMaster University have discovered how to make human blood from adult human skin.
Cell & Microbiology
Nov 7, 2010
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0
Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA ...
Cell & Microbiology
Jun 6, 2024
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8
Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells (HSCs) are remarkably long-lived. HSCs are blood-forming cells—they give rise to rapidly dividing progenitor cells, which in turn ...
Cell & Microbiology
Apr 30, 2024
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60
Scientists have solved a cellular murder mystery nearly 25 years after the case went cold. Following a trail of evidence from fruit flies to mice to humans revealed that cannibalistic cells likely cause a rare human immunodeficiency. ...
Cell & Microbiology
Jan 7, 2024
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98
Bone may seem as if it's a hard, lifeless structure, but now the cells living within have been imaged in unprecedented detail, thanks to an innovative imaging method developed at the Garvan Institute of Medical Research.
Cell & Microbiology
Oct 26, 2023
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2
Researchers at Tel Aviv University have destroyed 90% of multiple myeloma blood cancer cells under laboratory conditions, and 60% in human tissues taken from patients at Rabin Medical Center (Belinson Hospital), using an ...
Bio & Medicine
Jul 31, 2023
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89
More than 215 million years ago, a large amphibian species lived in floodplains in southwestern Poland: Metoposaurus krasiejowensis. On one of these fossils, Polish and American scientists, with the participation of researchers ...
Evolution
Dec 22, 2022
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