Customized programming of human stem cells

Induced pluripotent stem cells (iPS) have the potential to convert into a wide variety of cell types and tissues for drug testing and cell replacement therapies. However, the "recipes" for this conversion are often complicated ...

How stem cells choose their careers

"What do you want to be when you grow up?" is a question it seems like every child gets asked. A few precocious ones might answer "a doctor" or "an astronaut," but most will probably smile and shrug their shoulders. But well ...

Nanoparticles can turn off genes in bone marrow cells

Using specialized nanoparticles, MIT engineers have developed a way to turn off specific genes in cells of the bone marrow, which play an important role in producing blood cells. These particles could be tailored to help ...

Super-potent blood stem cells discovered in human embryos

Stem cells that form the blood and immune system, so-called hematopoietic stem cells (HSCs), have important applications in the treatment of blood cancers and other diseases of the immune system. Through blood stem cell transplantation, ...

Turning off 'junk DNA' may free stem cells to become neurons

For every cell in the body there comes a time when it must decide what it wants to do for the rest of its life. In an article published in the journal PNAS, NIH researchers report for the first time that ancient viral genes ...

Scientists find optimal age of stem cells

Biophysicists from the Moscow Institute of Physics and Technology and Vladimirsky Moscow Regional Clinical Research Institute have determined the optimal age of reprogrammed stem cells suitable for restoring heart tissue. ...

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