Study identifies how blood stem cells maintain their fate

Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical ...

Metabolism found to regulate production of killer cells

In a recent study from Lund University in Sweden, researchers discovered that metabolic changes affect how blood cells are formed during embryonic development. They found a previously unknown metabolic switch with a key role ...

Researchers identify key regulator of blood stem cell development

A protein that masterminds the way DNA is wrapped within chromosomes has a major role in the healthy functioning of blood stem cells, which produce all blood cells in the body, according to a new study from researchers at ...

The point of no return: Chromatin enforces cell fate decisions

Stem cells balance self-renewal with differentiation into mature cells. A fundamental and intriguing question is when during the process of maturation a cell reaches a "point of no return," losing its capacity to self-renew ...

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