A team at NDORMS has developed a new approach to significantly improve the accuracy of RNA sequencing. They have pinpointed the primary source of inaccurate quantification in both short and long-read RNA sequencing, and have ...
Molecular & Computational biology
Feb 5, 2024
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13
Protein molecules lie at the heart of biology. Our typical understanding of proteins states that each type of protein has a specific three-dimensional shape that enables it to perform its function. This dogma is challenged ...
Molecular & Computational biology
Jan 31, 2024
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27
In a groundbreaking study, researchers have unveiled a previously unknown conformational state of a crucial transporter protein, OxlT, which plays a vital role in preventing kidney stone formation. This discovery, achieved ...
Biochemistry
Jan 29, 2024
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46
Scientists working on biological design should focus on the idiosyncrasies of biological systems over optimization, according to new research.
Biotechnology
Jan 19, 2024
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105
In nature, organic molecules are either left- or right-handed, but synthesizing molecules with a specific "handedness" in a lab is hard to do. Make a drug or enzyme with the wrong "handedness," and it just won't work. Now ...
Analytical Chemistry
Jan 10, 2024
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100
Sequencing all of the RNA in a cell can reveal a great deal of information about that cell's function and what it is doing at a given point in time. However, the sequencing process destroys the cell, making it difficult to ...
Biotechnology
Jan 10, 2024
0
9
Image-based plant phenotyping has become crucial in understanding plant biology and agriculture. However, distinguishing relevant biological structures from the background remains a challenge, particularly in low-contrast ...
Molecular & Computational biology
Dec 20, 2023
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0
The Pomoideae subfamily includes nutritionally valuable pome fruits like apples and pears, and their genetic diversity is critical for the enhancement of fruit crops. Current research has made strides in intergeneric hybridization ...
Molecular & Computational biology
Nov 21, 2023
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0
Biological materials are made of individual components, including tiny motors that convert fuel into motion. This creates patterns of movement, and the material shapes itself with coherent flows by constant consumption of ...
General Physics
Nov 20, 2023
0
88
A new mathematical model predicts that mammalian sperm cells have two distinct swimming modes. This prediction opens new questions about potential connections between sperm cells' motor activity and their transitions to hyperactivation ...
General Physics
Nov 6, 2023
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