NASA researchers battle biofilm in space

A small group of scientists on the biofilm mitigation team at NASA's Marshall Space Center in Huntsville, Alabama, study solutions to combat fast-growing colonies of bacteria or fungi, known as biofilm, for future space missions.

Researchers thwart resistant bacteria's strategy

Antibiotic resistant bacteria are experts in evolving new strategies to avoid being killed by antibiotics. One such bacterium is Pseudomonas aeruginosa, which is naturally found in soil and water, but also hospitals, nursing ...

Biologists determine bacteria sense damage to relatives

Carnegie Mellon University biologists have discovered that Vibrio cholerae, the bacteria behind the cholera disease, can sense when its relatives die. Bacterial cell death is often accompanied by lysis, where the cell explodes, ...

page 1 from 31

Biofilm

A biofilm is an aggregate of microorganisms in which cells are stuck to each other and/or to a surface. These adherent cells are frequently embedded within a self-produced matrix of extracellular polymeric substance (EPS). Biofilm EPS, which is also refered to as "slime," is a polymeric jumble of DNA, proteins and polysaccharides. Biofilms may form on living or non-living surfaces, and represent a prevalent mode of microbial life in natural, industrial and hospital settings . The cells of a microorganism growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which by contrast, are single-cells that may float or swim in a liquid medium. Microbes form a biofilm in response to many factors, which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics . When a cell switches to the biofilm mode of growth, it undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated .

This text uses material from Wikipedia, licensed under CC BY-SA