Nasty nanoinjectors pose a new target for antibiotic research

If you've ever suffered the misery of food poisoning from a bacterium like Shigella or Salmonella, then your cells have been on the receiving end of "nanoinjectors"—microscopic spikes made from proteins through which pathogens ...

The dynamic cytoskeleton in bacterial cell division

(Phys.org) —The cytoskeletal proteins of eukaryotes polymerize into self-organized patterns even as pure solutions. However, to see more complex dynamics, like filament sliding or rotation, various motor proteins and cofactors ...

Ice-cold methods decode bacterial infection systems

When attacking body cells, bacteria, such as salmonellae or Yersinia (plague pathogens), inject specific bacterial proteins through hollow, syringe-like structures – called injectisomes – into the host cells. These substances ...

Uncovering the tricks of nature's ice-seeding bacteria

Like the Marvel Comics superhero Iceman, some bacteria have harnessed frozen water as a weapon. Species such as Pseudomonas syringae have special proteins embedded in their outer membranes that help ice crystals form, and ...

Study finds new moves in protein's evolution

Highlighting an important but unexplored area of evolution, scientists at The Scripps Research Institute (TSRI) have found evidence that, over hundreds of millions of years, an essential protein has evolved chiefly by changing ...

It takes a(n academic) village to determine an enzyme's function

Scientists have sequenced the genomes of nearly 6,900 organisms, but they know the functions of only about half of the protein-coding genes thus far discovered. Now a multidisciplinary effort involving 15 scientists from ...

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