(Bio)sensing protein interactions

The job of a protein hub inside the nucleus of a cell is similar to that of a chef in a kitchen. Both need to manage multiple tasks efficiently for a successful outcome. For the chef, if they spend too much time chopping ...

Cell mechanics research is making chemotherapy friendlier

Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body. The mechanical properties of prostate cancer cells treated with the most commonly used anti-cancer ...

New tool removes chemotherapy drugs from water systems

'What goes in, must come out' is a familiar refrain. It is especially pertinent to the challenges facing UBC researchers who are investigating methods to remove chemicals and pharmaceuticals from public water systems.

Single-cell test can reveal precisely how drugs kill cancer cells

Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time. To combat this evasive behavior, researchers have developed a method named D2O-probed ...

Scientists discover new anti-cancer molecule

A group of Moscow scientists has discovered and explained the activity mechanism of a new anti-cancer molecule—diphenylisoxazole. This molecule has been shown to be effective against human cancer cells. The research, published ...

Nanopore reveals shape-shifting enzyme linked to catalysis

University of Groningen scientists have observed the characteristics of a single enzyme inside a nanopore. They learned that the enzyme can exist in four different folded states, or conformers, that play an active role in ...

Protecting DNA origami for anti-cancer drug delivery

Scientists have designed and synthesized chains of molecules with a precise sequence and length to efficiently protect 3-D DNA nanostructures from structural degradation under a variety of biomedically relevant conditions. ...

Cells protect themselves against stress by keeping together

Cell-to-cell contacts are necessary for the survival of human cells under protein-damaging conditions and stress. This was one of the conclusions made by a research team working under the leadership of Lea Sistonen, Professor ...

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