Neurotoxicological hazard assessment without animal testing

The development of our nervous system in the womb and during the first years of life is a highly complicated process: Nerve cells proliferate by cell division, specialize, change their position in the tissue and interconnect ...

Researchers identify key player in cellular response to stress

An enzyme called Fic, whose biochemical role was discovered at UT Southwestern more than a dozen years ago, appears to play a crucial part in guiding the cellular response to stress, a new study suggests. The findings, published ...

Inhibiting key metabolic enzyme shows promise against melanoma

Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. Published in Nature Cell Biology, ...

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