New research results from Uppsala University, Sweden, show that the key to treating neurodegenerative prion diseases such as mad cow disease and Creutzfeldt-Jakob disease may lie in the ribosome, the protein synthesis machinery ...
Biochemistry
Jul 2, 2013
0
0
Most proteins have a single 'correct' way to fold; typically, improperly folded proteins are promptly eliminated by cells. However, certain misfolded proteins have a tendency to aggregate in dense fibrous clumps known as ...
Cell & Microbiology
Oct 5, 2012
0
0
(Phys.org)—In collaboration with colleagues at Oxford, a team of researchers at Umeå University in Sweden has now further elaborated its discovery of a way to detect Parkinson's disease at an early stage, and applications ...
Biochemistry
Sep 26, 2012
0
0
More than half of all cases of dementia in the elderly can be attributed to Alzheimer's disease. Despite vast research efforts, an effective therapy has not been developed, and treatment consists of dealing with the symptoms. ...
Biochemistry
Jan 12, 2012
0
0
Massachusetts General Hospital researchers say they have determined how iron contributes to the production of brain-destroying plaques found in Alzheimer's patients.
Biochemistry
Oct 6, 2010
3
0
A major discovery is challenging accepted thinking about amyloids - the fibrous protein deposits associated with diseases such as Alzheimer's and Parkinson's - and may open up a potential new area for therapeutics.
Biochemistry
Dec 4, 2009
0
0
Amyloidosis is a multifaceted disease group caused by deposits of the misfolded "amyloid" protein in various tissues. Amyloid protein is very unique compared to other native proteins in that it has a cross-β-sheet structure, ...
Veterinary medicine
Oct 7, 2021
0
4
The hope is to be able, one day, to fight the pathogenic action of the amyloid-beta protein, whose build-up is associated with Alzheimer's disease. In the meantime, scientists—including a group from the International School ...
Biochemistry
Mar 30, 2015
0
21
Besides their tremendous value in treating high cholesterol and lowering the risk of heart disease, statins have also been reported to potentially lower the risks of other diseases, such as dementia. However, a study in the ...
Biochemistry
Oct 28, 2009
0
0
Researchers have found that a technique used to visualize amyloid fibers in the laboratory might have the potential to destroy them in the clinic. The technique involves zapping the fluorescently-tagged fibers with a laser, ...
Jan 7, 2009
0
0
