Proteins barge in to turn off unneeded genes

(Phys.org)—The sorcerer's apprentice started a water-carrying system, but couldn't stop it, and soon he was up to his neck in water, and trouble. Living cells have a better design: When they activate a gene, they have a ...

Researchers reveal largest catalog of gene activators

University of Toronto researchers have created a first-in-class functional catalog of proteins that activate gene expression, with implications for tailored therapy for cancer and other diseases that occur when wrong genes ...

Designer molecule detects tiny amounts of cyanide, then glows

(PhysOrg.com) -- A small molecule designed to detect cyanide in water samples works quickly, is easy to use, and glows under ultraviolet or "black" light. Although the fluorescent molecule is not yet ready for market, its ...

Infrared sensor as new method for drug discovery

Using an infrared sensor, biophysicists at Ruhr-Universität Bochum (RUB) have succeeded in analysing quickly and easily which active agents affect the structure of proteins and how long that effect lasts. Thus, Prof Dr. ...

Imaging method reveals a 'symphony of cellular activities'

Within a single cell, thousands of molecules, such as proteins, ions, and other signaling molecules, work together to perform all kinds of functions—absorbing nutrients, storing memories, and differentiating into specific ...

Solving the mystery of what puts sperm 'in the mood'

In a potential advance toward a male contraceptive pill and new treatments for infertility, researchers are reporting the identification of key biochemical changes that put sperm “in the mood” for fertilization.

Biochemists zero in on key molecules that enable cells to crawl

Biochemists have made a discovery that sheds light on the molecular machinery that allows some cells, such as immune cells or even malignant cancer cells in humans, to wiggle their way through tissues like organs, skin or ...

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