See also stories tagged with Drug discovery
University of Birmingham scientists have developed a new material that changes from a gel to a liquid-like state under ultraviolet light and can be rebuilt using heat or dismantled by acid.
A research team has developed a new molecular editing strategy that can directly convert pyridine compounds into their positional isomers. Instead of moving individual substituents around the molecule, the method relocates ...
The complete genome of the tuberculosis bacterium was sequenced and published in 1998. Since then, scientists have deciphered about two-thirds of TB's genes. Or have they?
Iron is essential. Our cells need it to produce energy, carry oxygen throughout the body and power countless chemical reactions that sustain life. But this metal has a dark side. When too much of it is left free inside cells, ...
Scientists often describe life as a series of chemical reactions. Pallav Kosuri, Ph.D., describes life as movement. Chemical reactions are how you drive the movement of atoms, proteins, cells and bodies—without movement, ...
Every 15 minutes, someone in the U.S. dies from a drug-resistant superbug. A few decades from now, antibiotic-resistant bacterial infections threaten to become the leading cause of death worldwide, outpacing cancer.
Like a delivery driver navigating crowded city streets, a gene-therapy-toting lipid nanoparticle faces a gauntlet of potential detours on its journey toward a cell's nucleus. First, there's entering the cell's plasma membrane; ...
Designing an effective antibody drug is like searching for the right key in a warehouse of locks. Scientists may begin with millions—or even billions—of antibody candidates, but only a tiny fraction will recognize and bind ...
Long before humans discovered biodegradable plastics, microorganisms had already invented their own. Many bacteria and archaea produce natural bioplastics called polyhydroxyalkanoates (PHAs), storing them inside their cells ...
Researchers at the University of Wisconsin–Madison have developed a simpler way to produce a fast-growing class of targeted cancer therapies, a discovery that could make the medicines easier to manufacture consistently while ...
