Search results for CRISPR-Cas9

Biotechnology Sep 22, 2025

Compact Cas9d enzyme revealed as promising genome-editing tool

A research team led by Prof. Wang Yanli from the Institute of Biophysics of the Chinese Academy of Sciences has revealed the structure and mechanism of a highly active Type II-D Cas9, offering a promising new tool for genome ...

Biotechnology Sep 18, 2025

Inspired by bacteria's defense strategies, scientists develop chemical DNA tagging for genome editing

A research team led by scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) has introduced a new way to fine-tune genetic material. Their study, published in Nature Biotechnology, describes an innovative ...

Biotechnology Sep 18, 2025

Small nuclear RNA base editing offers a safer alternative to CRISPR, researchers find

Genetic editing holds promise to treat incurable diseases, but the most popular method—CRISPR—sometimes does more harm than good. A new study from University of California San Diego and Yale University researchers highlights ...

Evolution Sep 17, 2025

From fish cloaca to fingers: Scientists trace the origin of our digits

How did digits evolve? While it is clear that they derive from genetic programs already present in fish, their precise origin remains a matter of debate. An international team led by the University of Geneva (UNIGE) with ...

Cell & Microbiology Sep 17, 2025

DNA folding more important for cell function than previously thought

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production. This discovery challenges ...

Biotechnology Sep 17, 2025

New Cas9 proteins dramatically lower the error rate of prime editing

A genome-editing technique known as prime editing holds potential for treating many diseases by transforming faulty genes into functional ones. However, the process carries a small chance of inserting errors that could be ...

Biotechnology Sep 16, 2025

CRISPRgenee: New method leads to a better understanding of cell functions

The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as "gene scissors," which enables researchers to better understand how human cells function and stay healthy. Researchers ...

Biochemistry Sep 10, 2025

Triggering RNA activation on demand: Strategy expands options for therapeutics and gene editing

National University of Singapore (NUS) researchers have devised a method to safely and temporarily "switch off" and then "turn on" ribonucleic acid (RNA) inside cells. This is achieved using structurally optimized disulfide-containing ...

Biotechnology Sep 9, 2025

Scientists develop faster technique to uncover hidden gene switches

Researchers at the Max Delbrück Center have developed a new method to discover how DNA controls genes. Their technique, published in Cell Genomics, can reveal the genetic "switches" that regulate important genes more quickly ...

Cell & Microbiology Sep 4, 2025

CRISPR study reveals surprising role of Cas9 as guardian of bacterial defense

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they'd stumbled upon a revolutionary tool researchers could use to edit the DNA of ...

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