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Peppercorn-sized clumps of human brain cells grown in a lab for a record seven years aged similarly to those inside our heads, suggesting they "recorded the passage of time," scientists said Wednesday.
The human brain is often described as one of the most complex structures in biology, and much of its power comes from how it's organized. Its outer layer, the cerebral cortex, is not one uniform sheet. As the brain develops, ...
An interdisciplinary team of engineers and chemists at Penn State has laid the groundwork for 3D printing spheroids—tiny clusters of living cells—capable of regenerating bone tissue in response to severe trauma or infections.
Researchers at Karolinska Institutet and Stockholm University have developed a new tool that estimates a cell's biological age by analyzing its gene activity. In an article published in the journal Advanced Science, they ...
The deoxyribonucleic acid (DNA) of living organisms contains regulatory elements that control when, where and to what extent specific genes are turned on or off. They can be co-opted to create "gene switches" that hold significant ...
Scientists often describe life as a series of chemical reactions. Pallav Kosuri, Ph.D., describes life as movement. Chemical reactions are how you drive the movement of atoms, proteins, cells and bodies—without movement, ...
Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research have demonstrated in a biomedical study that ribosomes, the protein factories of our cells, face an unusually ...
A joint research team—led by professor Young Seok Cho from the School of Medicine, alongside professor James J. Moon from the University of Michigan—has developed the world's first oral, microbiome-based nanomedicine. By ...
When a wound does not heal properly, it leaves a scar. Similarly, mutations—which are permanent changes to genetic code—are often the result of damaged DNA that has not been properly repaired. Mutations can impede the function ...
How readily a cell divides and how well it survives are fundamental to life, shaping everything from organ size to the body's ability to withstand disease. That combination, known as cell fitness, isn't the same for everyone. ...
