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Bio & Medicine Oct 5, 2022

Will silicon nitride and common chemistry help revolutionize genomic sequencing?

Genomic sequencing has revolutionized our understanding of medicine and evolution, such as identifying hereditary anomalies. Arrays of nanometer-sized holes—nanopores—in silicon nitride can in principle dramatically speed ...

Other Oct 3, 2022

Sweden's Paabo wins medicine Nobel for sequencing Neanderthal DNA

Swedish paleogeneticist Svante Paabo, who sequenced the genome of the Neanderthal and discovered the previously unknown hominin Denisova, on Monday won the Nobel Medicine Prize.

Ecology Sep 7, 2022

New insight into selecting appropriate primers and databases when sequencing soil nematode DNA

Soil nematodes represent a major component of soil communities in terrestrial ecosystems, and play an important role in regulating nutrient cycling and soil health. High-throughput sequencing technology is increasingly used ...

Cell & Microbiology Aug 22, 2022

Scientists scrutinize changes in germline DNA structure that lay the groundwork for embryo development

Totipotency is the ability of a cell to develop into an individual through elaborate processes of embryogenesis and is created during the development of the precursors of sperm and eggs, which are called germline cells. Understanding ...

Cell & Microbiology Aug 22, 2022

How mitochondrial dysfunction leads to premature aging and disease

Researchers at the University at Buffalo and their collaborators have developed powerful new ways to study and potentially reverse the cellular mechanisms that cause mitochondrial diseases and premature aging.

Evolution Aug 16, 2022

Statistical tool finds 'gaps' in DNA data sets shouldn't be ignored

A simple statistical test shows that contrary to current practice, the "gaps" within DNA protein and sequence alignments commonly used in evolutionary biology can provide important information about nucleotide and amino acid ...

Biotechnology Aug 9, 2022

Mathematical method enables extraction of clear signals from single-cell RNA sequencing data

Since scientists first mapped the complete human genome, attention has now turned to the question of how cells use this master copy of genetic instructions. It is known that when genes are switched on, parts of the DNA sequences ...

Biotechnology Aug 8, 2022

Artificial intelligence tools predict DNA's regulatory role and 3D structure

Newly developed artificial intelligence (AI) programs have accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies ...

Superconductivity Aug 2, 2022

In DNA, scientists find solution to building superconductor that could transform technology

Scientists at the University of Virginia School of Medicine and their collaborators have used DNA to overcome a nearly insurmountable obstacle to engineer materials that would revolutionize electronics.

Biochemistry Jul 27, 2022

Programming pH: New technique could accelerate DNA synthesis

pH—the concentration of protons in a watery solution—indicates how acidic the solution is. It regulates a broad range of natural and engineered chemical processes, including the synthesis of designed DNA sequences for applications ...

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