Search results for CRISPR

Biotechnology Apr 13, 2021

Scaling up genome editing in tiny worms

Understanding the effects of specific mutations in gene regulatory regions—the sections of DNA and RNA that turn genes on and off—is important to unraveling how the genome works, as well as normal development and disease. ...

Biotechnology Apr 12, 2021

Researchers call for greater awareness of unintended consequences of CRISPR gene editing

Researchers at the Francis Crick Institute have revealed that CRISPR-Cas9 genome editing can lead to unintended mutations at the targeted section of DNA in early human embryos. The work highlights the need for greater awareness ...

Biotechnology Apr 9, 2021

New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged

Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to organisms' DNA. While the system could potentially be useful in treating a ...

Plants & Animals Apr 7, 2021

Research suggests eucalyptus trees can be genetically modified not to invade native ecosystems

Eucalyptus, a pest-resistant evergreen valued for its hardy lumber and wellness-promoting oil, can be genetically modified not to reproduce sexually, a key step toward preventing the global tree plantation staple from invading ...

Biotechnology Apr 5, 2021

CRISPR-SNP-chip enables amplification-free electronic detection of single point mutations

Keck Graduate Institute (KGI) Assistant Professor and University of California, Berkeley Visiting Scientist Dr. Kiana Aran first introduced the CRISPR-Chip technology in 2019. Now just two years later, she has expanded on ...

Biotechnology Mar 30, 2021

Prime editing enables precise gene editing without collateral damage

The latest gene editing technology, prime editing, expands the 'genetic toolbox' for more precisely creating disease models and correcting genetic problems, scientists say.

Biotechnology Mar 29, 2021

Understanding how cells repair DNA may lead to targeted cancer treatments

The human body is made up of trillions of cells that divide throughout a person's lifetime. Each time a cell divides, its genetic material is copied and reproduced so the duplicate carries the same information. This process ...

Biotechnology Mar 29, 2021

Study reports six novel variants for CRISPR-Cas12a in plants, expanding genome engineering

In a new publication in Nature Communications, associate professor of Plant Science at the University of Maryland Yiping Qi continues to innovate genome editing and engineering in plants, with the ultimate goal of improving ...

Biotechnology Mar 22, 2021

Upgrade for CRISPR/Cas: Researchers knock out multiple genes in plants at once

Using an improved version of the gene editing tool CRISPR/Cas9, researchers knocked out up to twelve genes in plants in a single blow. Until now, this had only been possible for single or small groups of genes. The approach ...

Biotechnology Mar 11, 2021

Scientists develop novel gene editor to correct disease-causing mutations

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause ...

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