Search results for CRISPR-Cas9

Biotechnology Nov 25, 2022

New function of CRISPR gene scissors discovered: Protein scissors activate defense function

For several years now, the CRISPR/Cas9 gene scissors have been causing a sensation in science and medicine. This new tool of molecular biology has its origins in an ancient bacterial immune system. It protects bacteria from ...

Biotechnology Nov 24, 2022

New CRISPR-based tool inserts large DNA sequences at desired sites in cells

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

Biotechnology Nov 16, 2022

New technique for studying liver cells within an organism could shed light on the genes required for regeneration

The liver's ability to regenerate itself is legendary. Even if more than 70% of the organ is removed, the remaining tissue can regrow an entire new liver.

Biotechnology Nov 14, 2022

New study finds that CRISPR/Cas9 leads to unexpected genomic changes

The widely used gene scissor (CRISPR/Cas) can modify the genetic content in cells to study the molecular roles of genes and has gained great clinical relevance in gene therapy to treat genetic diseases. A new study performed ...

Cell & Microbiology Nov 8, 2022

Scientists unveil the functional landscape of essential genes

A team of scientists at Whitehead Institute and the Broad Institute of MIT and Harvard have systematically evaluated the functions of more than 5,000 essential human genes using a novel, pooled, imaged-based screening method. ...

Biotechnology Oct 28, 2022

Breakthrough in CRISPR research may lead to more effective and safer gene editing

10 years ago we saw a breakthrough in modern biology.

Biochemistry Oct 27, 2022

Team develops a prodrug form of curcumin that shows anti-tumor effects without toxicities

Curcumin, a natural molecule related to turmeric, has been used to treat cancer patients in cancer clinical studies. While it has documented antitumor effects, challenges involving its chemistry have caused drug development ...

Cell & Microbiology Oct 24, 2022

Even good gene edits can go bad

A Rice University lab is leading the effort to reveal potential threats to the efficacy and safety of therapies based on CRISPR-Cas9, the Nobel Prize-winning gene editing technique, even when it appears to be working as planned.

Evolution Oct 21, 2022

Characterizing the cis-regulatory evolution of the gene WntA in nymphalid butterflies

A combined team of researchers from Cornell University and The George Washington University, has characterized the cis-regulatory evolution of the gene WntA in nymphalid butterflies. In their study, published in the journal ...

Biotechnology Oct 11, 2022

New CRISPR-Cas approach permits more precise DNA cleavage

A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies. The recent innovation, which is published in Nature ...

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