An international team led by researchers from the University Medical Center Göttingen (UMG), Germany, has used advanced electron microscopy technologies to capture key cellular mechanisms of stress resistance with near-atomic ...
A drug to treat Parkinson's disease can be made from waste plastic bottles using a pioneering method, a study shows. The approach harnesses the power of bacteria to transform post-consumer plastic into L-DOPA, a frontline ...
Alzheimer's disease affects millions of people around the world. To study this condition, researchers must peer inside the distinctive environment of the human brain. but for scientists to get the most accurate picture of ...
Mitochondria are essential for cell survival, repair, and adaptation. Not only do they generate most of the energy needed during a cell's life, but they also regulate cell death, calcium balance, and responses to stress. ...
After more than a decade of research, scientists have discovered the natural mechanism behind a novel form of cell death called ferroptosis. The work, described in the current issue of Cell, points toward an entirely new ...
A novel method to manipulate the inner structure of cells connects several scientific fields and could represent a significant step in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. ...
Cornell researchers have discovered a new way cells regulate how they respond to stress, identifying an interaction between two proteins that helps keep a critical cellular recycling system in balance. The findings show that ...
A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top 200 small-molecule drugs ...
Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is known to regulate cytosolic-side functions such as membrane fusion/fission, movement, and membrane-contact ...
A new study from Bar-Ilan University shows that one of sleep's core functions originated hundreds of millions of years ago in jellyfish and sea anemones, among the earliest creatures with nervous systems. By tracing this ...
