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Cell & Microbiology Jan 29, 2021

The force to shape an organ

Carnegie Mellon University professor of biomedical engineering and materials science and engineering Adam Feinberg, along with postdoctoral fellow Dan Shiwarski and graduate student Joshua Tashman, have created a novel biosensor ...

Cell & Microbiology Jan 26, 2021

Iron-carrying extracellular vesicles are key to respiratory viral-bacterial co-infection

The mechanism by which acute viral respiratory infections promote secondary bacterial growth and infection in the airways depends on iron-carrying extracellular sacs secreted by the cells lining the host's airways, report ...

Biochemistry Jan 25, 2021

Platinum complex inhibits metastasis through conformational modulation of heparan sulfate

Cisplatin has been used to treat cancer since the 1970s. Since then, many other platinum-containing cytostatic drugs have been developed, such as triplatinNC, a highly charged complex that contains three ligand-bridged platinum ...

Biotechnology Jan 18, 2021

Promoting axon regeneration in the zebrafish spinal cord

After an injury to the spinal cord, patients often remain paralyzed because damaged nerve tracts do not regrow due to the formation of scar tissue. Scientists from the Max Planck Institute for the Science of Light in Erlangen, ...

Cell & Microbiology Jan 12, 2021

New functions of integrin and talin discovered by an international research network

Researchers at Tampere University, Finland, have published new results in collaboration with an international research network that help to understand the biological phenomena mediated by cell membrane integrin receptors ...

Biochemistry Dec 31, 2020

Light-responsive E. coli functional biofilms as scaffolds for hydroxyapatite mineralization

Living organisms have evolved mechanisms of biomineralization to build structurally ordered and environmentally adaptive composite materials. While research teams have significantly improved biomimetic mineralization research ...

Biochemistry Dec 11, 2020

Hydrogel controls cell growth outside the body

Chemists at Radboud University discovered a unique material in 2013. From a synthetic polymer named polyisocyanopeptide (PIC), they made a gel that behaves similar to the matrix that surrounds the cells in your body. The ...

Molecular & Computational biology Dec 11, 2020

Expression, diffusion and molecular interactions determine Wnt3 distribution

An interdisciplinary team of physicists and biologists from NUS has characterized the mechanism by which Wnt3, a key regulator in neural patterning and brain development, spreads to long distances in the developing zebrafish ...

Cell & Microbiology Dec 10, 2020

Embryonic development in a petri dish: 3-D cell culturing technique could replace mouse embryos

By growing mouse stem cells in a special gel, a Berlin research team succeeded in producing structures similar to parts of an embryo. The trunk-like structures develop the precursors for neural, bone, cartilage and muscle ...

Cell & Microbiology Dec 1, 2020

Watch immune cells dig tunnels in tissues

White blood cells called cytotoxic T lymphocytes (CTLs) dig tunnels in tissues, potentially allowing other CTLs to quickly reach infected cells and tumor cells, researchers report December 1st in Biophysical Journal. The ...

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