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Search results for fluorescence microscopy

Biochemistry May 31, 2017

Supercomputer simulations to design rigid fluorescent molecules for clarifying protein structure and dynamics

Most methods for the structural characterization of biomolecules, such as X-ray crystallography or electron microscopy, require static or crystallized samples. Attaching fluorescent molecules to protein surfaces, however, ...

Cell & Microbiology Nov 23, 2016

Bright red fluorescent protein created

After years of trying, biologists have succeeded in creating an extremely bright red fluorescent protein in the lab. This is good news for researchers, including cancer and stem cell researchers, who use fluorescent proteins ...

Nanophysics Sep 27, 2016

Researchers design wearable microscope that can measure fluorescent dyes through skin

UCLA researchers working with a team at Verily Life Sciences have designed a mobile microscope that can detect and monitor fluorescent biomarkers inside the skin with a high level of sensitivity, an important tool in tracking ...

Cell & Microbiology Dec 11, 2023

Integrating AI with super-resolution microscopy for advancements in cellular biology

In 2014, the Nobel Prize in Chemistry celebrated the breakthroughs in super-resolution microscopy, a technology that allows us to capture highly detailed images of small parts of cells using fluorescent microscopy. Despite ...

Biochemistry Nov 12, 2020

Illuminating tiny proteins in living cells using single-residue labeling tags

SciLifeLab Fellow Simon Elsässer laboratory at Karolinska Institutet reports a method, which allows fluorescent tagging of proteins with the small perturbation—a single amino acid—added genetically on either end of a ...

Cell & Microbiology Oct 5, 2023

New microscopy method can help put sharper focus on plankton samples

A new method developed by EMBL scientists can help us identify and investigate plankton species in field samples with greater speed, accuracy, and resolution than ever possible before.

Optics & Photonics Mar 10, 2023

High-speed super-resolution microscopy via temporal compression

As an indispensable tool for observing the microcosmos, optical microscopy has boosted the development of various fields, including biology, medicine, physics, and materials. However, optical diffraction imposes a spatial ...

Optics & Photonics Apr 21, 2022

Researchers demonstrate label-free super-resolution microscopy

Researchers have developed a new measurement and imaging approach that can resolve nanostructures smaller than the diffraction limit of light without requiring any dyes or labels. The work represents an important advance ...

Biotechnology Sep 13, 2021

New method enables 3D microscopy of human organs

Researchers at Umeå University now demonstrate a method by which specific cell types in human organs can be studied with micrometer precision. The method can be used to reveal previously unrecognized alterations in the pancreas, ...

Optics & Photonics Dec 3, 2020

Supercharge your microscope: Researchers share guide for ultra-precise 3-D imaging

UNSW Sydney researchers have shared step-by-step instructions to empower other scientists to enhance the resolution and stability of single-molecule microscopes.

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