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Biochemistry Jan 7, 2025

Fluorescent RNA complexes offer new insights into cellular dynamics

The specific labeling of RNA in living cells poses many challenges. In a new article published in the journal Nature Chemical Biology, researchers from the University of Innsbruck describe a structure-guided approach to the ...

Optics & Photonics Jan 7, 2025

AI technique generates clear images of thick biological samples without additional hardware

Depth degradation is a problem biologists know all too well: The deeper you look into a sample, the fuzzier the image becomes. A worm embryo or a piece of tissue may only be tens of microns thick, but the bending of light ...

Cell & Microbiology Dec 23, 2024

Researchers uncover core components of xylan synthase complex in rice

Xylan is a major interlocking polysaccharide in the cell walls of seed plants, possessing a high structural diversity and cellular specificity in terms of chain polymerization, side chains, and modifications.

Analytical Chemistry Dec 10, 2024

Reshaping tradition: Experts share why commonly used measuring method for fluorescence is not always appropriate

Fluorescence is a well-known phenomenon with many practical applications that has been studied for decades. Despite this, a commonly used mathematical formalism to describe how it evolves over time does not make physical ...

Optics & Photonics Dec 9, 2024

Quantum mechanical principle of strong coupling leads to better optical sensors

A team of researchers from the University of Cologne, Hasselt University (Belgium) and the University of St Andrews (Scotland) has succeeded in using the quantum mechanical principle of strong light-matter coupling for an ...

Cell & Microbiology Dec 4, 2024

Scientists discover interactions between molecular machines, potentially offering opportunities for drug development

Choosing a film for a movie night is always a battle. Now imagine if you could pick one that provided a window into some of the most fundamental biological processes that keep us alive. For the first time ever, researchers ...

Bio & Medicine Nov 27, 2024

New imaging platform advances 3D visualization of cellular structures at the nanoscale

A team of researchers led by Anna-Karin Gustavsson at Rice University has developed an innovative imaging platform that promises to improve our understanding of cellular structures at the nanoscale.

Optics & Photonics Nov 20, 2024

Megapixel fluorescence microscopy through scattering layers made simple

A team from The Hebrew University of Jerusalem has introduced a new method for megapixel-scale fluorescence microscopy through complex scattering media. This approach resolves high-resolution images from several tens of widefield ...

Molecular & Computational biology Nov 19, 2024

Deep learning architecture enables higher efficiency in light microscopy image improvement

It is the computational processing of images that reveals the finest details of a sample placed under all kinds of different light microscopes. Even though this processing has come a long way, there is still room for improvement, ...

Cell & Microbiology Nov 14, 2024

Picky proteins: Understanding yeast adaptor protein selectivity

The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis.

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