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Biotechnology Sep 23, 2024

New approach may yield modified messenger RNAs for treating a wide range of conditions

The life-saving use of messenger RNA (mRNA) in COVID-19 vaccines was a public example of the potential of mRNA-based therapies, which hold great promise for a wide range of treatment applications from cancer immunotherapy ...

Space Exploration Sep 2, 2024

Q&A: Scientist discusses the MESSENGER mission to Mercury

Twenty years ago, the MESSENGER mission revolutionized our understanding of Mercury. We sat down with project head and former Carnegie Science director Sean Solomon to talk about how the mission came together and the groundbreaking ...

Cell & Microbiology Sep 2, 2024

Cells use alternative splicing to regulate gene expression, research suggests

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism increases the diversity of ...

Cell & Microbiology Aug 26, 2024

Viruses can work where antibiotics don't—new research tells us more about how they fight bacteria

As the globe faces a rise in antibiotic-resistant bacteria—making traditional antibiotics ineffective—specific viruses could offer a solution.

Biotechnology Aug 14, 2024

Light-responsive gene regulation at the mRNA level

Researchers at the University of Bayreuth have established a new optogenetic approach that can control the bacterial production of proteins at the mRNA level using blue light. The new system gates the activation of the genetic ...

Bio & Medicine Jul 29, 2024

New and improved drug-delivery molecules for skeletal muscle

Researchers from Tokyo Metropolitan University have created a new drug-delivery molecule, a zwitterionic polymer complex that can help get plasmid DNA inside cells when injected into skeletal muscle, a crucial step in the ...

Biochemistry Jul 18, 2024

Discovery of a tRNA modification enzyme that also acts on nucleosides

The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating ...

Biotechnology Jul 18, 2024

Gene silencing tool has a need for speed: Research provides deeper insight into RNAi tool design

RNA interference (RNAi) is a process that many organisms, including humans, use to decrease the activity of target RNAs in cells by triggering their degradation or slicing them in half. If the target is a messenger RNA, the ...

General Physics Jul 12, 2024

What flavor is that neutrino? Adding flavor helps to track neutrino movement in astrophysical systems

Neutrinos have a quantum mechanical property called "flavor." This flavor can transform as neutrinos move through space. A major challenge is to keep track of both the physical movement of the neutrinos and their change of ...

Cell & Microbiology Jul 10, 2024

Unexpected phage protein function discovered in bacteria battle

An unexpected find has enabled important progress to be made in the battle against harmful bacteria. An international team of researchers, led by Professor Peter Fineran from the University of Otago, investigated a particular ...

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