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Biotechnology Sep 23, 2024

Compact 'gene scissors' enable effective genome editing, may offer future treatment of high cholesterol gene defect

CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known "gene scissors" but is much smaller and thus easier to transport into cells.

Biochemistry Sep 23, 2024

Chemists discover new ways in which single-celled organisms organize their DNA

It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden Ph.D. candidate Samuel Schwab has found that the histones in these organisms ...

Materials Science Sep 17, 2024

Synthetic mini-motor: Researchers convert chemical energy into rotational energy at the supramolecular level

Researchers at the Technical University of Munich (TUM) have developed an artificial motor at the supramolecular level that can develop impressive power. This wind-up motor is a tiny ribbon made of special molecules. When ...

Cell & Microbiology Sep 4, 2024

Scientists uncover diverse marine microbes with potential for new antibiotics and plastic breakdown

New research shows how oceans can be used to help address major challenges such as the shortage of antimicrobial medicines, solutions for plastic pollution and novel enzymes for genome editing.

Evolution Aug 21, 2024

Ancient microbes linked to evolution of human immune proteins

When you become infected with a virus, some of the first weapons your body deploys to fight it are those passed down to us from our microbial ancestors billions of years ago. According to new research from The University ...

Evolution Aug 15, 2024

How researchers reconstructed the ancestor of all life on Earth

Understanding how life began and evolved on Earth is a question that has fascinated humans for a long time, and modern scientists have made great advances when it comes to finding some answers. Now, our recent study hopes ...

Ecology Aug 14, 2024

Earth's oldest, tiniest creatures are poised to be climate change winners—and the repercussions could be huge

The world's oceans are home to microscopic organisms invisible to the human eye. The tiny creatures, known as "prokaryotes," comprise 30% of life in the world's oceans.

Molecular & Computational biology Aug 9, 2024

Researchers find β-d-manno-heptoses are immune agonists across kingdoms

Bacterial small molecule metabolites, such as adenosine-diphosphate-d-glycero-β-d-manno-heptose (ADP-heptose) and their derivatives, act as effective innate immune agonists in mammals.

Plants & Animals Aug 8, 2024

DNA Topoisomerase insights hold potential for drug discovery and plant protection

Insights into the function of DNA Topoisomerase VI (Topo VI) may provide a springboard for drug discovery and crop protection.

Molecular & Computational biology Aug 6, 2024

Researchers identify over 2,000 potential toxins using machine learning

In a novel study, researchers have unveiled new secrets about a fascinating bacterial weapon system that acts like a microscopic syringe. The research paper, titled "Identification of novel toxins associated with the extracellular ...

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