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Researchers have developed a practical strategy for recovering biosynthetic information from fragmented metagenomic data. Through this work, the researchers identified and prioritized promising natural-product candidates ...
Whether in drug discovery, environmental analysis or metabolomics: anyone analyzing complex biological samples often needs to identify the small molecules they contain. Researchers at Friedrich Schiller University Jena, in ...
When scientists assess how dangerous a bacterium is, the first question often seems simple: Can it be stopped or killed? In microbiology and antibiotic research, one of the classic readouts has been whether a bacterium can ...
How do bacteria adapt when resources run low? ISTA researchers have found that, under starvation stress, E. coli can use bacteriophages and CRISPR-Cas immunity to transfer and incorporate DNA, accelerating genetic reshuffling. ...
A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle's diversity across multiple branches on the tree of complex life. With major contributions from ...
In water, soil and air all around us lives a free-living, single-celled organism called Acanthamoeba. Most of the time, Acanthamoeba keeps to itself. On rare occasions, though, the amoeba infects humans and can cause severe ...
A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation. But until now, scientists weren't ...
For centuries, historians have drawn the boundaries of where ancient people lived based on the evidence they left behind. By studying their remains, burial practices and other archaeological clues, they can determine the ...
Viruses come in two major flavors—not chocolate and vanilla, quips Harvard Medical School structural biologist Stephen Harrison, but those enveloped in membranes, such as herpesvirus, influenza virus, HIV and SARS-CoV-2, ...
The bacterium Chlamydia trachomatis is one of the most common causes of sexually transmitted infections worldwide. Biologically, it is regarded as a highly specialized "nutrient thief": Because chlamydia have lost the ability ...
