Natural systems such as CRISPR-associated transposons (CASTs) offer a targetable, one-step way to edit genomes. However, adapting them for biomedical applications has been challenging.
In a development that could help protect one of the world's most beloved agricultural commodities, a research team at Penn State has successfully created disease-resistant cacao plants using gene-editing technology. According ...
Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is turned on, the production of proteins or other substances is promoted; when it's turned off, production ...
A research team led by Prof. Wang Yanli from the Institute of Biophysics of the Chinese Academy of Sciences has revealed the structure and mechanism of a highly active Type II-D Cas9, offering a promising new tool for genome ...
Genetic editing holds promise to treat incurable diseases, but the most popular method—CRISPR—sometimes does more harm than good. A new study from University of California San Diego and Yale University researchers highlights ...
Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production. This discovery challenges ...
The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as "gene scissors," which enables researchers to better understand how human cells function and stay healthy. Researchers ...
Every minute, all around us, battles are fought on a microscopic level. Bacteriophages (also known as phages) are viruses that infect and kill bacteria. Just like viruses that infect us, these phages seek to steal the resources ...
Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential housekeeping process, autophagy ...
When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they'd stumbled upon a revolutionary tool researchers could use to edit the DNA of ...
