Research unlocks molecular key to animal evolution and disease
The dawn of the Animal Kingdom began with a collagen scaffold that enabled the organization of cells into tissues.
The dawn of the Animal Kingdom began with a collagen scaffold that enabled the organization of cells into tissues.
Cell & Microbiology
Apr 19, 2017
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480
Researchers at Vanderbilt University Medical Center have mapped the conformational changes that occur in a protein "notorious" for pumping chemotherapeutic drugs out of cancer cells and blocking medications from reaching ...
Biochemistry
Mar 13, 2017
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In a new study, Vanderbilt pharmacologist Jerod Denton, Ph.D., Ohio State entomologist Peter Piermarini, Ph.D., and colleagues report an experimental molecule that inhibits kidney function in mosquitoes and thus might provide ...
Ecology
Dec 5, 2016
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904
Chloride plays a key role in the formation of the basement membrane, a suprastructure on the outside of cells that undergirds and guides the function of most of the tissues of the body.
Cell & Microbiology
May 23, 2016
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217
The "brush border" β a densely packed array of finger-like projections called microvilli β covers the surfaces of the cells that line our intestines.
Cell & Microbiology
Apr 16, 2014
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A chemical bond discovered by Vanderbilt University scientists that is essential for animal life and which hastened the "dawn of the animal kingdom" could lead to new therapies for cancer and other diseases.
Evolution
Dec 16, 2013
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A fungus that is killing frogs and other amphibians around the world releases a toxic factor that disables the amphibian immune response, Vanderbilt University investigators report Oct. 18 in the journal Science.
Plants & Animals
Oct 17, 2013
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(Phys.org)βOn the front lines of our defenses against bacteria is the protein calprotectin, which "starves" invading pathogens of metal nutrients.
Plants & Animals
Feb 21, 2013
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2
An old pinworm medicine is a new lead in the search for compounds that block a signaling pathway implicated in colon cancer. The findings, reported by Vanderbilt University Medical Center researchers in the November issue ...
Biochemistry
Nov 19, 2010
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Researchers led by Vanderbilt's Roger Cone, Ph.D., have discovered a new member of a gene family that has powerful influences on pigmentation and the regulation of body weight.
Biotechnology
Oct 29, 2010
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