A multidrug efflux pump in motion

Researchers at Vanderbilt University Medical Center have mapped the conformational changes that occur in a protein "notorious" for pumping chemotherapeutic drugs out of cancer cells and blocking medications from reaching ...

Experimental insecticide explodes mosquitoes, not honeybees

In a new study, Vanderbilt pharmacologist Jerod Denton, Ph.D., Ohio State entomologist Peter Piermarini, Ph.D., and colleagues report an experimental molecule that inhibits kidney function in mosquitoes and thus might provide ...

Chloride 'switch' turns on membrane formation

Chloride plays a key role in the formation of the basement membrane, a suprastructure on the outside of cells that undergirds and guides the function of most of the tissues of the body.

Researchers develop antibodies to fight chikungunya virus

In late 2013 the Caribbean had its first case of the mosquito-borne chikungunya virus. Today there have been almost 1.2 million cases in 44 countries or territories, including 177 cases in 31 U.S. States.

Ancient chemical bond may aid cancer therapy

A chemical bond discovered by Vanderbilt University scientists that is essential for animal life and which hastened the "dawn of the animal kingdom" could lead to new therapies for cancer and other diseases.

Frog-killing fungus paralyzes amphibian immune response

A fungus that is killing frogs and other amphibians around the world releases a toxic factor that disables the amphibian immune response, Vanderbilt University investigators report Oct. 18 in the journal Science.

Blood-sucking superbug prefers taste of humans

"Staph" bacteria feed on blood. They need the iron that's hidden away inside red blood cells to grow and cause infections. It turns out that these microbial vampires prefer the taste of human blood, Vanderbilt University ...

page 2 from 3