AI technology generates original proteins from scratch

Scientists have created an AI system capable of generating artificial enzymes from scratch. In laboratory tests, some of these enzymes worked as well as those found in nature, even when their artificially generated amino ...

Social interactions override genetics when birds learn new songs

New UC San Francisco research finds that although young male songbirds are genetically predisposed to sound like their fathers, enriched early experience with a foster-father can overcome this genetic destiny. This finding ...

CRISPR-based tool maps gene function in human cells

UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.

Deadly fungus uses unexpected system to control its virulence

A research team led by UC San Francisco scientists has discovered a cellular signaling system that regulates the virulence of Cryptococcus neoformans, a fungus that has been estimated to cause nearly a million cases of meningitis ...

Shouldering the burden of evolution

As early humans increasingly left forests and utilized tools, they took an evolutionary step away from apes. But what this last common ancestor with apes looked like has remained unclear. A new study led by researchers at ...

Chimpanzee 'mini-brains' hint at secrets of human evolution

At some point during human evolution, a handful of genetic changes triggered a dramatic threefold expansion of the brain's neocortex, the wrinkly outermost layer of brain tissue responsible for everything from language to ...

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