Big-data analysis points toward new drug discovery method

A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been ...

From strands to droplets—new insights into DNA control

A host of proteins and other molecules sit on the strands of our DNA, controlling which genes are read out and used by cells and which remain silent. This aggregation of genetic material and controlling molecules, called ...

Rare cells are 'window into the gut' for the nervous system

Specialized cells in the gut sense potentially noxious chemicals and trigger electrical impulses in nearby nerve fibers, according to a new study led by UC San Francisco scientists. "These cells are sensors, like a window ...

New tool illuminates cell signaling pathways key to disease

In a major advance for fundamental biological research, UC San Francisco scientists have developed a tool capable of illuminating previously inscrutable cellular signaling networks that play a wide variety of roles in human ...

How computers are searching for drugs of the future

Drug discovery may bring to mind images of white lab coats and pipettes, but when Henry Lin, PhD, recently set out to find a better opioid with fewer side effects, his first step was to fire up the computers.

Study shows how skates, rays and sharks sense electrical fields

Sharks, rays and skates can hunt for prey hidden in the sandy sea floor by "listening" for faint traces of bioelectricity—they can literally sense their prey's heart beating. The basic anatomy of the electro-sensory organs ...

page 3 from 10