Sanford Burnham Prebys Medical Discovery Institute (SBP) is an non-profit medical research institute with locations in La Jolla, California and Orlando, Florida. There are more than 850 scientists at SBP blending cutting-edge fundamental research with robust drug discovery to address unmet clinical needs in the areas of cancer, neuroscience, immunity, and metabolic disorders.
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Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. Published in Nature Cell Biology, ...
Cell & Microbiology
Sep 1, 2022
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Scientists at Sanford Burnham Prebys have gained a deeper insight into the intricacies of autophagy, the process in which cells degrade and recycle cellular components. The findings, published in Current Biology, describe ...
Cell & Microbiology
Jun 18, 2021
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Scientists at Sanford Burnham Prebys Medical Discovery Institute have taken a deep dive into a previously overlooked family of proteins and discovered that they are essential to maintaining the energy that cells need to grow ...
Cell & Microbiology
May 12, 2021
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Scientists at Sanford Burnham Prebys have identified, at an atomic level, how a part of a protein called PLEKHA7 interacts with a cell's membrane to regulate important intercellular communications.
Biochemistry
Apr 20, 2021
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Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that fruit flies that spent several weeks on the International Space Station (ISS)—about half of their lives—experienced profound structural ...
Space Exploration
Nov 25, 2020
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People who live more than 110 years, called supercentenarians, are remarkable not only because of their age, but also because of their incredible health. This elite group appears resistant to diseases such as Alzheimer's, ...
Biotechnology
Mar 20, 2020
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Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that worms live longer lives if they produce excess levels of a protein, p62, which recognizes toxic cell proteins that are tagged for destruction. ...
Molecular & Computational biology
Dec 11, 2019
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278
For the modern biologist, large-scale OMICs studies—which map all of the genes, proteins, RNA and more that underlie a biological system—are standard tools of the trade. But interpreting these big-data outputs to generate ...
Biotechnology
Apr 3, 2019
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There are many times when our cells need to move. Mobile cells guide our body's formation (embryonic development). Immune cells roam to capture unwanted intruders. And healing cells (fibroblasts) migrate to mend wounds. But ...
Bio & Medicine
Jan 11, 2019
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255
Investigators at Burnham Institute for Medical Research (Burnham), Mount Sinai School of Medicine (Mount Sinai), the Salk Institute for Biological Studies (Salk) and the Genomics Institute of the Novartis Research Foundation ...
Cell & Microbiology
Dec 22, 2009
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