Beyond average: New platforms genetically barcode tens of thousands of cells at a time
Imagine someone hands you a smoothie and asks you to identify everything that went into it.
Imagine someone hands you a smoothie and asks you to identify everything that went into it.
Biotechnology
May 21, 2015
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High-throughput sequencing has turned biologists into voracious genome readers, enabling them to scan millions of DNA letters, or bases, per hour. When revising a genome, however, they struggle, suffering from serious writer's ...
Biotechnology
Jul 26, 2009
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For more than half a century, studies on the African clawed frog (Xenopus laevis) have helped scientists better understand the biological underpinnings of life, from embryonic development and neurobiology to genetics and ...
Plants & Animals
Dec 21, 2017
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Researchers have discovered in fruit flies a key metabolic hormone thought to be the exclusive property of vertebrates. The hormone, leptin, is a nutrient sensor, regulating energy intake and output and ultimately controlling ...
Cell & Microbiology
Sep 27, 2012
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A first-of-its-kind analysis of historical DNA ties tens of thousands of living people to enslaved and free African Americans who labored at an iron forge in Maryland known as Catoctin Furnace soon after the founding of the ...
Biotechnology
Aug 3, 2023
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Scientists have discovered a possible new way to fight COVID-19 by turning part of SARS-CoV-2 against itself.
Cell & Microbiology
Feb 22, 2022
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142
(Phys.org) —A boy with cystic fibrosis develops a chronic and potentially deadly Burkholderia dolosa infection in his lungs. Varieties of genetic mutations allow some strains of the bacteria to survive the dual assaults ...
Biotechnology
Dec 13, 2013
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Under a microscope, the first few hours of every multicellular organism's life seem incongruously chaotic. After fertilization, a once tranquil single-celled egg divides again and again, quickly becoming a visually tumultuous ...
Cell & Microbiology
Oct 1, 2020
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118
Tremendous controversy erupted in early 2014 when two papers published in Nature described how a technique called "stimulus-triggered acquisition of pluripotency," or STAP, could quickly and efficiently turn ordinary cells ...
Cell & Microbiology
Sep 23, 2015
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350
Bacteria live in a state of perpetual warfare, with different species battling for dominion over their competitors and when pathogen, over their infected host. New research suggests that the human pathogen Vibrio cholerae, ...
Cell & Microbiology
Feb 29, 2012
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