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Nanoparticles can genetically modify several human cell types

In a demonstration that could help pave the way for gene therapies with fewer side effects, several human cell types have been genetically modified with protein nanoparticles designed at University of Michigan Engineering ...

How graphene oxide kills bacteria while sparing human cells

Hygiene in everyday items that touch the body—such as clothing, masks, and toothbrushes—is critically important. The underlying principle of how graphene selectively eliminates only bacteria has now been revealed. In Advanced ...

Magnetic microbots steer quantum sensors inside living cells

Cells are squishy and soft. Tiny nanometer-sized particles such as quantum sensors cannot move freely inside them due to viscous drag, which makes sensing challenging. Researchers at the Indian Institute of Science (IISc) ...

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Bio & Medicine
Engineered nanoparticles show enhanced intrinsic luminescence for biomedical imaging and cancer treatment
Bio & Medicine
Prodrug lipid nanoparticle could unlock universal immunotherapy for solid cancers
Bio & Medicine
Liquid biopsy method uses nanoparticle Raman signals to separate two lookalike enzymes
Bio & Medicine
Engineered lipid nanoparticles reprogram immune metabolism for better mRNA vaccines
Bio & Medicine
Researchers explore new ways to neutralize germs using light-activated nanomaterials
Bio & Medicine
Photonics and nanotech could spot cancer signals 5 to 8 years earlier
Bio & Medicine
Milk-derived nanoparticles may enable physicians to target aggressive bile duct cancer
Bio & Medicine
Gold nanoclusters could selectively recognize chiral biomolecules to help detect certain diseases
Bio & Medicine
Breathing in nanoparticles could enable a 10-minute pneumonia check at point of care
Bio & Medicine
AI analysis of nanoribbon assembly reveals protein design principles
Bio & Medicine
Tiny tools, sharp aim: Nanobodies target tumors with precision
Bio & Medicine
Ultrasound-based approach to delivering potent drugs into cancer cells shows promise in benchtop experiments
Bio & Medicine
Diatom-based microrobots show promise for targeted photodynamic therapy of glioblastoma
Bio & Medicine
DNA origami vaccine rivals mRNA shots while being easier to store and manufacture
Bio & Medicine
DNA barcoding reveals which gene-therapy nanoparticles reach targets in vivo
Bio & Medicine
Simple 'cocktail' of amino acids dramatically boosts power of mRNA therapies and CRISPR gene editing
Bio & Medicine
Trouble swallowing? A nanogel tweak may keep therapeutic stem cells alive longer
Bio & Medicine
Biodegradable nanoparticles can seek and destroy diseased immune cells
Bio & Medicine
Researchers track mineral growth on bioorganic coatings in real time at nanoscale
Bio & Medicine
Robotic microfluidic platform brings AI to lipid nanoparticle design

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Environment
Reducing aircraft soot might not actually reduce the climate effects of contrails
Archaeology
Thirty previously unpublished verses by Empedocles discovered on a papyrus from Cairo
Evolution
Researchers present first fossilized 'emperor' butterfly
Veterinary medicine
Oregano, rosemary and 'time': Long-term swine study shows natural-compound benefits
Earth Sciences
Lakes forming next to Greenland's melting ice sheet are speeding up glacier flow
Astrobiology
High nickel concentrations in Martian bedrock point to potential biosignatures
Analytical Chemistry
Stretching metals can tune catalysis: A new method predicts energy shifts
Earth Sciences
Chaos shapes how meandering rivers change over time, research shows
Evolution
Fins, fingers and toes: A new take on repeating body parts and how they come to be
Astronomy
Gravitational waves suggest a 'forbidden zone' for stellar-origin black holes
Molecular & Computational biology
Accuracy test for protein language models shines light into AI 'black box'
Astronomy
Unexplained sky flashes from the 1950s: Independent analysis supports their existence
Optics & Photonics
Hidden features in X-rays could radically change how we measure and understand them
Condensed Matter
Superconductivity switched on in material once thought only magnetic
Cell & Microbiology
Atomic-level simulations reveal rotational mechanism behind a critical biomolecular motor
Condensed Matter
Helical liquid crystals can flip light's chirality under ultralow electric fields
Evolution
New model shows how behavioral flexibility affects animal evolution
Earth Sciences
Conflict-driven farmland abandonment in Syria leads to land uplift, study finds
Earth Sciences
Why subduction zones act as the Earth's 'gold kitchens'
Evolution
Free software lets laptops simulate how aging evolves under selection

Decoding new DNA 'letters' to advance medicine and biotechnology

A research team led by the A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a method to accurately and efficiently read DNA containing non-standard bases—a task once thought too complex for conventional DNA ...