In their effort to understand the very earliest stages of life and how they can go wrong, scientists are confronted with ethical issues surrounding the use of human embryos. The use of animal embryos is also subject to restrictions ...
Cell & Microbiology
Apr 23, 2021
1
16
Protocols that allow the transformation of human induced pluripotent stem cell (iPSC) lines into organoids have changed the way scientists can study developmental processes and enable them to decipher the interplay between ...
Biotechnology
Jun 18, 2020
0
223
During the past decade, the gene editing tool CRISPR has transformed biology and opened up hopeful avenues to correct deadly inherited diseases. Last fall, scientists began the first human clinical trials using CRISPR to ...
Biotechnology
Jan 30, 2020
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286
A pioneering new study led by Florida State University biologists could fundamentally change our understanding of how embryonic stem cells differentiate into specific cell types.
Cell & Microbiology
Jun 20, 2019
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1
A team of researchers at Tufts University School of Medicine developed a method to grow and maintain olfactory stem cells in culture, which can then be used to restore tissue in the nose. The discovery raises hope that future ...
Biochemistry
Mar 28, 2019
1
174
IUPUI biologists, growing human pluripotent stem cell-derived retinal ganglion cells in the lab, have developed a way to create more-mature models that better mimic the environment in the human retina. By introducing hPSC-RGCs ...
Cell & Microbiology
Jan 25, 2019
0
151
In two newly published papers, a scientific team at Case Western Reserve University School of Medicine reports on the discovery and implementation of a new, more efficient method for generating an important brain stem cell ...
Cell & Microbiology
Oct 1, 2018
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230
Researchers from the University of California, Irvine have identified intrinsic cell properties that influence the fate of neural stem cells, affecting what type of brain cell they will form: neurons, astrocytes, or oligodendrocytes. ...
Cell & Microbiology
Sep 6, 2018
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164
MCL-1 is a member of the BCL-2 family of proteins important for blocking apoptosis, or programmed cell death. Many types of cancer cells escape the body's effort to kill them by overexpressing MCL-1.
Cell & Microbiology
Mar 23, 2018
0
134
In work that brings researchers closer to the goal of precision medicine approaches to treating glaucoma and other neurodegenerative vision diseases, a new IUPUI study has, for the first time, been able to identify a wide ...
Cell & Microbiology
Mar 22, 2018
0
93
