Stem cells have more reserves for DNA replication

In cell division, nothing is as important as the precise replication of billions of genetic letters that make up DNA. Since this genomic integrity is so fundamental to survival, scientists had assumed that replication mechanisms ...

KeyGenes can predict future identity of human fetal stem cells

A snapshot of gene activity is now all that's necessary to determine what organ or tissue type that a cluster of fetal stem cells will ultimately become. An algorithm developed by a team of Dutch scientists makes it possible ...

OSKM stoichiometry determines iPS cell reprogramming

Researchers at Kyoto University's Center for iPS Cell Research and Application discover a simple way to increase the production of induced pluripotent stem cells. A major hurdle in reprogramming science is generating a sufficient ...

Reduction of germ cells yields more zebrafish males

Temasek Life Sciences Laboratory, Hokkaido University and Ehime University are pleased to announce that their researchers have discovered that the reduction of gonadal stem cells will yield more male zebrafish. The article ...

Scientists find way to 'keep the lights on' for cell self-renewal

One remarkable quality of pluripotent stem cells is they are immortal in the lab, able to divide and grow indefinitely under the right conditions. It turns out this ability also may exist further down the development path, ...

Time-lapse study reveals bottlenecks in stem cell expansion

A time-lapse study of human embryonic stems cells has identified bottlenecks restricting the formation of colonies, a discovery that could lead to improvement in their use in regenerative medicine.

One step closer to cell reprogramming

In 2012, John B. Gurdon and Shinya Yamakana were awarded the Nobel Prize in medicine for discovering that adult cells can be reprogrammed into pluripotent ones (iPS); the cells obtained are capable of behaving in a similar ...

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