A new software tool allows researchers to quickly query datasets generated from single-cell sequencing. Users can identify which cell types any combination of genes are active in. Published in Nature Methods on 1st March, ...
Cell & Microbiology
Mar 3, 2021
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23
The latest developments in fluorescence microscopy make it possible to image individual molecules in cells or molecular complexes with a spatial resolution of up to 20 nanometres. However, under certain circumstances, an ...
Optics & Photonics
Feb 26, 2021
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28
Scientists at the University of Groningen (The Netherlands), in collaboration with colleagues from the University of Torino (Italy), have developed a method to visualize and quantify alternative structures of RNA molecules. ...
Biotechnology
Feb 22, 2021
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10
With every passing day, human technology becomes more refined and we become slightly better equipped to look deeper into biological processes and molecular and cellular structures, thereby gaining greater understanding of ...
Bio & Medicine
Feb 17, 2021
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73
Cryo-electron microscopy (cryo-EM) allows scientists to produce high-resolution, three-dimensional images of tiny molecules such as proteins. This technique works best for imaging proteins that exist in only one conformation, ...
Molecular & Computational biology
Feb 4, 2021
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26
Researchers have found a simple way to eliminate almost all sequencing errors produced by a widely used portable DNA sequencer, potentially enabling scientists working outside the lab to study and track microorganisms like ...
Cell & Microbiology
Jan 12, 2021
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325
Columbia researchers have created a new technology using synthetic llama antibodies to prevent specific proteins from being destroyed inside cells. The approach could be used to treat dozens of diseases, including cystic ...
Cell & Microbiology
Dec 7, 2020
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18
Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's ...
Biotechnology
Oct 20, 2020
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269
We've all seen that moment in a cop TV show where a detective is reviewing grainy, low-resolution security footage, spots a person of interest on the tape, and nonchalantly asks a CSI technician to "enhance that." A few keyboard ...
Molecular & Computational biology
Oct 8, 2020
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213
Scientists have developed a new technique using tools made of luminescent DNA, lit up like fireflies, to visualize the mechanical forces of cells at the molecular level. Nature Methods published the work, led by chemists ...
Biochemistry
Sep 22, 2020
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191
