Optical tweezers untangle chemotherapy agent's impact on DNA
New Cornell research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish.
New Cornell research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish.
Biochemistry
Jan 30, 2023
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24
A research team led by Professor Xiang David Li from the Department of Chemistry at The University of Hong Kong (HKU) has developed a novel chemical tool to reveal how bacteria adapt to the host environment and control host ...
Biochemistry
Jan 30, 2023
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24
Scientists at the Max Planck Institute for Marine Microbiology reveal how a methane-generating microbe can grow on toxic sulfite without becoming poisoned.
Cell & Microbiology
Jan 19, 2023
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17
In multicellular organisms, there are three types of protein glycosylation. N-glycosylation, O-mannosylation and C-mannosylation. All of these processes take place in the endoplasmic reticulum, and in all of them enzymes ...
Biochemistry
Jan 16, 2023
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84
COVID-19 has had a lasting global health impact that continues to challenge the health care system. As the coronavirus continues to mutate, the current COVID-19 prevention strategies are plagued with supply chain disruptions, ...
Biochemistry
Nov 29, 2022
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32
A new collaborative study from the University of Eastern Finland, Washington University in St. Louis, University of Wisconsin–Madison, University of North Carolina at Chapel Hill and the Promega Corporation discloses the ...
Biochemistry
Nov 28, 2022
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15
The world's aging population, the growing burden of chronic and infectious diseases, and the emergence of novel pathogens have made the need for new treatments more urgent than ever. Yet, discovering a new drug and bringing ...
Biochemistry
Nov 16, 2022
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40
The latest developmental drugs, particularly for use in oncology, rely on the targeted degradation of harmful pathogenic proteins. In a recent study published in Nature Chemical Biology, researchers at CeMM, the Research ...
Biochemistry
Nov 3, 2022
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32
Tuberculosis, an infectious disease that killed 1.5 million people in 2020, is most commonly treated with a cocktail of four drugs that must be taken for up to six months. This treatment plan, however, can have the unintended ...
Biochemistry
Oct 6, 2022
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104
A new drug designed by scientists at Scripps Research can turn the COVID-19 virus into a harbinger of its own doom.
Biochemistry
Sep 29, 2022
0
803