How plants respond to heat stress

Plants, like other organisms, can be severely affected by heat stress. To increase their chances of survival, they activate the heat shock response, a molecular pathway also employed by human and animal cells for stress protection. ...

Old protein, new function: tBID can directly trigger cell death

The protein tBID can trigger programmed cell death (apoptosis) by inducing damage in the energy suppliers of the cells, the mitochondria. Apoptosis is essential for maintaining tissue balance. In addition, apoptosis plays ...

Autophagy in major human diseases

In a consensus article, Federico Pietrocola, at the Department of Biosciences and Nutrition, KI, and colleagues explore the pathophysiological relevance of autophagy in human illnesses, while highlighting the therapeutic ...

Identification of two pathways for SARS-CoV-2 entry into cells

SARS-CoV-2 is the virus that has caused the COVID-19 pandemic. Ideally, to prevent its spread, treatments should target the early stages of infection before the virus penetrates cells. A joint investigation by INRAE and Heidelberg ...

How SARS coronaviruses reprogram host cells to their own benefit

Coronavirus researchers led by Professor Rolf Hilgenfeld of the University of Luebeck and PD Dr. Albrecht von Brunn of the Ludwig-Maximilian Universitaet (LMU) in Munich have discovered how SARS viruses enhance the production ...

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