Cell Chemical Biology (previously, Chemistry & Biology) publishes reports of novel investigations in all areas at the interface of chemistry and biology. Chemistry & Biology strongly encourages submission of articles in which chemical tools are used to provide unique insight into biological function and mechanism. Studies that illustrate the underlying chemistry of biological processes will also be viewed favorably. Other relevant studies of interest to chemists and biologists will also be considered. In general, to be considered suitable for publication in this journal, investigations that primarily have a genetic, computational, or theoretical focus must contain substantiating experimental data. All articles should not only be of significance to the immediate field but should also be of interest to our diverse readership from the broad chemical-biology community.
Scripps Research chemists Hans Renata, Ph.D., and Alexander Adibekian, Ph.D., have discovered a way to efficiently create a synthetic version of a valuable natural compound called cepafungin I, which has shown promise as ...
Biochemistry
21 hours ago
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390
All cells have a lipid membrane that encircles their internal components—forming a protective barrier to control what gets in and what stays out. The proteins embedded in these membranes are essential for life; they help ...
Biochemistry
Dec 19, 2019
0
153
When cells suffer DNA damage, they send out an SOS signal. When the repair crew arrives, the emergency signal is cancelled as it is no longer needed. This two-stage process is an important one in many different diseases, ...
Molecular & Computational biology
Nov 11, 2019
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12
Selecting the most effective molecules for drug delivery is often a trial-and-error process, but Cornell engineers are providing some precision thanks to a technique that reveals the performance of those molecules inside ...
Biochemistry
Nov 02, 2019
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123
Human medicines that act on important signal systems in the brain make fish bolder, shows a new study on three-spined sticklebacks by researchers at Linköping University. The results reinforce that the signal substances ...
Plants & Animals
Oct 17, 2019
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80
Onions, cabbage, garlic. While nutritious, eating these foods can lead to an embarrassing side effect: smelly flatulence. More than just smelly, hydrogen sulfide, the chemical compound responsible for the rotten-egg aroma, ...
Biochemistry
Oct 07, 2019
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108
Staphylococcus aureus bacteria are a major cause of serious infections that often persist despite antibiotic treatment, but scientists at the UNC School of Medicine have now discovered a way to make these bacteria much more ...
Biochemistry
Aug 14, 2019
0
344
In the search for new weapons against malaria, most drug development has focused on the parasites that cause the disease. But Duke University researchers are trying a different tack. Instead of targeting the malaria parasite ...
Biochemistry
Jun 27, 2019
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0
An estimated 1.7 million Americans suffer from substance abuse disorders related to opioid use for pain relief, according to the National Institute on Drug Abuse. This causes an economic burden of more than $78 billion per ...
Biochemistry
May 16, 2019
1
77
Malaria treatment resistance could be avoided by studying how resistance evolves during drug development, according to a new paper published in Cell Chemical Biology.
Biochemistry
May 09, 2019
0
22
