Cell Chemical Biology (previously, Chemistry & Biology) publishes reports of novel investigations in all areas at the interface of chemistry and biology. Chemistry & Biology strongly encourages submission of articles in which chemical tools are used to provide unique insight into biological function and mechanism. Studies that illustrate the underlying chemistry of biological processes will also be viewed favorably. Other relevant studies of interest to chemists and biologists will also be considered. In general, to be considered suitable for publication in this journal, investigations that primarily have a genetic, computational, or theoretical focus must contain substantiating experimental data. All articles should not only be of significance to the immediate field but should also be of interest to our diverse readership from the broad chemical-biology community.
The University of Konstanz team led by biologist Christof Hauck has discovered a novel inhibitor that locks tumor cells in place.
Cell & Microbiology
Apr 20, 2022
0
66
Pharmaceutical researchers speak of a hit when they come across a promising substance with a desired effect in early drug discovery. Unfortunately, hits are rarely bull's-eyes, often showing undesirable side effects that ...
Biochemistry
Jan 27, 2022
0
92
An FDA-approved drug for hepatitis C can increase bacterial sensitivity to antibiotics and reduce the likelihood of antibiotic resistance, according to a new study led by New York University researchers published in Cell ...
Biochemistry
Nov 23, 2021
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97
A study out of the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University has resulted in the discovery of a promising new antimalarial compound.
Biochemistry
Oct 27, 2021
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76
Recently, TANG Gongli's group from the Shanghai Institute of Organic Chemistry and University of Chinese Academy of Sciences reported the biosynthetic pathway of mechercharmycin A (MCM-A), a marine natural product belonging ...
Biochemistry
Sep 06, 2021
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14
Mutant DNA sequences inside cellular mitochondria can be eliminated using a bespoke chemical compound. The approach, developed by scientists at Kyoto University's Institute for Integrated Cell-Material Science (iCeMS) in ...
Cell & Microbiology
Aug 27, 2021
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197
Every year, more than 200 million people are infected with malaria, and nearly 500,000 die from the disease. Existing drugs can treat the infection, but the parasite that causes the disease has evolved resistance to many ...
Biochemistry
Aug 10, 2021
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312
In the latest of ongoing efforts to expand technologies for modifying genes and their expression, researchers in the lab of Neville Sanjana at New York University (NYU) and the New York Genome Center (NYGC) have developed ...
Cell & Microbiology
Aug 03, 2021
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246
When Alexander Flemming discovered a mold on a culture plate overgrown with bacteria in 1928, he did not expect to find one of the most widely used active substances: penicillin. Accidental discoveries and the identification ...
Biochemistry
Jul 22, 2021
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286
Researchers have developed a more efficient platform for studying proteins that play a key role in regulating gene expression. The approach uses engineered yeast cells to produce enzyme and histone proteins, conduct biochemical ...
Biochemistry
Jul 01, 2021
0
16
