Cell Chemical Biology (previously, Chemistry & Biology) publishes reports of novel investigations in all areas at the interface of chemistry and biology. Chemistry & Biology strongly encourages submission of articles in which chemical tools are used to provide unique insight into biological function and mechanism. Studies that illustrate the underlying chemistry of biological processes will also be viewed favorably. Other relevant studies of interest to chemists and biologists will also be considered. In general, to be considered suitable for publication in this journal, investigations that primarily have a genetic, computational, or theoretical focus must contain substantiating experimental data. All articles should not only be of significance to the immediate field but should also be of interest to our diverse readership from the broad chemical-biology community.

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DNA SOS: Understanding DNA signaling pathways

When cells suffer DNA damage, they send out an SOS signal. When the repair crew arrives, the emergency signal is cancelled as it is no longer needed. This two-stage process is an important one in many different diseases, ...

Fluorescent probes offer fuller view of drug delivery in cells

Selecting the most effective molecules for drug delivery is often a trial-and-error process, but Cornell engineers are providing some precision thanks to a technique that reveals the performance of those molecules inside ...

Human medicines affect fish behavior

Human medicines that act on important signal systems in the brain make fish bolder, shows a new study on three-spined sticklebacks by researchers at Linköping University. The results reinforce that the signal substances ...

How the colon prioritizes gas detox over energy use

Onions, cabbage, garlic. While nutritious, eating these foods can lead to an embarrassing side effect: smelly flatulence. More than just smelly, hydrogen sulfide, the chemical compound responsible for the rotten-egg aroma, ...

Malaria hijacks your genes to invade your liver

In the search for new weapons against malaria, most drug development has focused on the parasites that cause the disease. But Duke University researchers are trying a different tack. Instead of targeting the malaria parasite ...

Chemists ID possible addiction-free pain reliever

An estimated 1.7 million Americans suffer from substance abuse disorders related to opioid use for pain relief, according to the National Institute on Drug Abuse. This causes an economic burden of more than $78 billion per ...

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