Cell Chemical Biology (previously, Chemistry & Biology) publishes reports of novel investigations in all areas at the interface of chemistry and biology. Chemistry & Biology strongly encourages submission of articles in which chemical tools are used to provide unique insight into biological function and mechanism. Studies that illustrate the underlying chemistry of biological processes will also be viewed favorably. Other relevant studies of interest to chemists and biologists will also be considered. In general, to be considered suitable for publication in this journal, investigations that primarily have a genetic, computational, or theoretical focus must contain substantiating experimental data. All articles should not only be of significance to the immediate field but should also be of interest to our diverse readership from the broad chemical-biology community.
Staphylococcus aureus bacteria are a major cause of serious infections that often persist despite antibiotic treatment, but scientists at the UNC School of Medicine have now discovered a way to make these bacteria much more ...
Biochemistry
Aug 14, 2019
0
344
In the search for new weapons against malaria, most drug development has focused on the parasites that cause the disease. But Duke University researchers are trying a different tack. Instead of targeting the malaria parasite ...
Biochemistry
Jun 27, 2019
0
0
An estimated 1.7 million Americans suffer from substance abuse disorders related to opioid use for pain relief, according to the National Institute on Drug Abuse. This causes an economic burden of more than $78 billion per ...
Biochemistry
May 16, 2019
1
77
Malaria treatment resistance could be avoided by studying how resistance evolves during drug development, according to a new paper published in Cell Chemical Biology.
Biochemistry
May 09, 2019
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22
A team headed by Dr. Claudia Jessen-Trefzer of the University of Freiburg's Institute for Pharmaceuticals Sciences has identified a transport protein in mycobacteria that is responsible for the uptake of the nutrient L-arabinofuranose. ...
Cell & Microbiology
Apr 29, 2019
0
4
Researchers led by St. Jude Children's Research Hospital structural biologists have discovered how the cell switches on an executioner mechanism called necroptosis that induces damaged or infected cells to commit suicide ...
Cell & Microbiology
Apr 26, 2019
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7
Bacterial pathogens must acquire nutrient metals from the host to survive and cause disease. To counter infection, hosts attempt to starve bacteria by hiding metals away in a process called "nutritional immunity." Bacteria ...
Cell & Microbiology
Apr 15, 2019
0
5
One of the most common cancer-promoting genes, known as Myc, is also one of the most difficult to target with drugs. Scientists have long tried to develop drugs that block the Myc protein, but so far their efforts have not ...
Biochemistry
Mar 15, 2019
0
122
Scientists from the German Cancer Research Center (DKFZ) have succeeded in reconstructing biomolecules in their mirror-image form. The researchers' goal is to create a mirror-image artificial protein synthesis system. Their ...
Biochemistry
Mar 14, 2019
0
49
UC San Francisco researchers have for the first time developed a strategy for targeting a key molecule implicated in Parkinson's disease, opening up a potential new treatment strategy for the currently incurable movement ...
Biochemistry
Mar 07, 2019
0
325
