Page 17: Research news on viruses

Viruses are acellular infectious agents that depend entirely on host cellular machinery for replication and are therefore studied as a central topic in microbiology, virology, and infectious disease research. They consist minimally of a nucleic acid genome (DNA or RNA, single- or double-stranded, linear or circular) enclosed in a protein capsid, and in many cases a host-derived lipid envelope containing viral glycoproteins. Viral classification and research focus on genome organization, replication strategies, host range, tropism, mechanisms of cell entry and egress, immune evasion, and evolutionary dynamics, as well as their roles in pathogenesis, horizontal gene transfer, and biotechnology applications such as vectors and phage therapy.

VIRE: A global data platform to better understand viruses

Researchers have developed VIRE, a database that integrates approximately 1.7 million viral genomes derived from more than 100,000 metagenomes worldwide. Metagenomic data is obtained by comprehensively sequencing all DNA ...

Virus battles drug-resistant infections

It's an evolutionary battle, an endless competition for survival, that has spanned millions of years. Within this epic tale for the ages, the skillful characters are mighty, but very, very tiny—they're microscopic. It's bacteria ...

Fishing for phages in botanical gardens

Kompetensportalen, Lucat, Lupin, Lubas and LUCRIS. Those are the names of some of Lund University's administrative systems. They are now also the names of five new bacteriophages that have recently been discovered in the ...

Phages with fully-synthetic DNA can be edited gene by gene

A team led by University of Pittsburgh's Graham Hatfull has developed a method to construct bacteriophages with entirely synthetic genetic material, allowing researchers to add and subtract genes at will. The findings open ...

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