Page 13: Research news on viruses

Viruses are acellular infectious agents that depend entirely on host cellular machinery for replication and are therefore studied as a central topic in microbiology, virology, and infectious disease research. They consist minimally of a nucleic acid genome (DNA or RNA, single- or double-stranded, linear or circular) enclosed in a protein capsid, and in many cases a host-derived lipid envelope containing viral glycoproteins. Viral classification and research focus on genome organization, replication strategies, host range, tropism, mechanisms of cell entry and egress, immune evasion, and evolutionary dynamics, as well as their roles in pathogenesis, horizontal gene transfer, and biotechnology applications such as vectors and phage therapy.

Novel kirkovirus may be associated with colitis in horses

In a pilot study, researchers from North Carolina State University have found a novel kirkovirus that may be associated with colitis—and potentially small colon impactions—in horses. The study could offer a route to new therapies ...

VIRE: A global data platform to better understand viruses

Researchers have developed VIRE, a database that integrates approximately 1.7 million viral genomes derived from more than 100,000 metagenomes worldwide. Metagenomic data is obtained by comprehensively sequencing all DNA ...

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