Research news on viruses

Viruses are acellular infectious agents that depend entirely on host cellular machinery for replication and are therefore studied as a central topic in microbiology, virology, and infectious disease research. They consist minimally of a nucleic acid genome (DNA or RNA, single- or double-stranded, linear or circular) enclosed in a protein capsid, and in many cases a host-derived lipid envelope containing viral glycoproteins. Viral classification and research focus on genome organization, replication strategies, host range, tropism, mechanisms of cell entry and egress, immune evasion, and evolutionary dynamics, as well as their roles in pathogenesis, horizontal gene transfer, and biotechnology applications such as vectors and phage therapy.

Bacteria may identify a virus without recognizing its DNA

When a virus enters a cell, its top priority is to replicate its genome rapidly, creating new viruses to infect elsewhere. The host has the opposite priority: to destroy the virus, ideally before it can do any harm. Biology ...

Uncovering the structure of the poxvirus 'portal complex'

Poxviruses have a long history in human disease as well as medicine: The first-ever vaccine was developed to protect against smallpox, which has since been eradicated. Despite this, scientists still don't fully understand ...

The hunt for a natural molecule that can release cellular energy

All cells in the human body—and the motions they enable, from our beating hearts to our wiggling toes—use energy generated by a molecule called ATP. Its energy is thought to be released to fuel cellular processes in only ...

Scientists find hidden individuality in viral infections

An international team of researchers developed a new way to uncover hidden differences in how viruses infect and destroy individual microbial cells—solving a biological puzzle that has persisted for more than 80 years.

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